Cosentyx, which is known by its scientific name secukinumab, is a medication prescribed for a variety of autoimmune conditions including types of plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, enthesitis-related arthritis, hidradenitis suppurativa (HS), and non-radiographic axial spondyloarthritis.
It works as an immunosuppressant, reducing inflammation by targeting and decreasing the effects of specific chemical substances in the body.
The Science Behind Cosentyx
The active ingredient in Cosentyx, secukinumab, is a monoclonal antibody. This means it’s a type of protein made in a lab that can bind to specific targets in the body.
Cosentyx targets and blocks a protein called interleukin-17A (IL-17A), which plays an important role in the development of autoimmune conditions. People with these conditions tend to have higher levels of IL-17A, which contributes to inflammation, pain, swelling, and various skin issues.
Cosentyx considerably reduces these symptoms by inhibiting the activity of IL-17A and providing relief to those affected.
Approved Uses
The FDA has approved Cosentyx for several uses, such as treatment of:
- persons aged six and up with moderate to severe plaque psoriasis
- active psoriatic arthritis in individuals two years and older
- active ankylosing spondylitis in adults
It’s also approved for treating:
- active non-radiographic axial spondyloarthritis in adults showing signs of inflammation
- active enthesitis-related arthritis in those four years and older
- moderate to severe hidradenitis suppurativa in adults
It is possible that it will reduce the body’s ability to fight infections, despite the fact that it can alleviate the symptoms of diseases like these.
Side Effects and Risks
Common side effects of Cosentyx include diarrhea and symptoms resembling a common cold, such as a stuffy nose, sneezing, and a sore throat.
But it’s important to be aware of more serious side effects like allergic reactions, which can show up as:
- hives
- chest tightness
- difficulty breathing
- swelling of the throat, face, lips or tongue
Since Cosentyx can weaken the immune system, users may be more susceptible to infections. Symptoms of an infection to watch for include:
- fever
- chills
- muscle aches
- skin sores
- difficulty breathing
Before starting Cosentyx, discussing any history of tuberculosis or inflammatory bowel disease with a doctor is important.
Usage Instructions
If you are prescribed Cosentyx, following your doctor’s instructions closely is necessary.
It comes in a form that can be self-administered through a subcutaneous injection, which means it’s injected under the skin.
Before injecting, let the medicine reach room temperature for 15 to 30 minutes but do not heat it using any external methods.
The injection can be given in various areas but avoid injecting into skin that is hard, red, or affected by psoriasis. After use, dispose of syringes properly for safety.
Precautions and Interactions
Before beginning treatment with Cosentyx, screening for tuberculosis is necessary due to an increased risk of reactivating this condition. Patients with active TB should not use Cosentyx.
Additionally, those with a latex allergy need to be cautious due to the natural rubber latex in the removable cap of the Sensoready pen and prefilled syringes.
As for vaccinations, live vaccines should be avoided during treatment with Cosentyx, but non-live vaccines like the COVID-19 vaccine are generally safe.
It’s important for your healthcare provider to know about all medications and vaccines you’ve had or intend to get. This is to keep potential interactions at bay.
Takeaways
Cosentyx is a targeted therapy that is intended for individuals who are afflicted with specific autoimmune conditions.
Although it provides relief from symptoms by inhibiting specific proteins that are responsible for inflammation, it is important to be aware of potential adverse effects, interactions, and precautions.
Always seek the advice of a qualified medical professional to come up with the most effective and secure treatment plan.
For more information, visit Canadian Pharmacy
You may also read
